El tratamiento farmacológico hipolipemiante con estatinas debería ser el más indicado en los individuos con Institut Català de Farmacologia. REVISIONES. Interacciones medicamentosas de agentes hipolipemiantes: aproximación para establecer y valorar su relevancia clínica. Revisión estructurada. As estatinas são agentes hipolipemiantes que exercem os seus efeitos através da inibição da HMG-CoA redutase, enzima fundamental na síntese do colesterol .

Author: Kidal Mumuro
Country: Estonia
Language: English (Spanish)
Genre: Art
Published (Last): 6 June 2011
Pages: 320
PDF File Size: 1.44 Mb
ePub File Size: 13.35 Mb
ISBN: 775-5-58794-240-5
Downloads: 91336
Price: Free* [*Free Regsitration Required]
Uploader: Malaramar

How to cite this article. Rhabdomyolysis associated with concomitant use of simvastatin and clarithromycin. Erythromycin coadministration increases plasma atorvastatin concentrations. Am J Med ; Risk for myopathy with statin therapy in high-risk patients. Rhabdomyolysis due to probable interaction between simvastatin and ritonavir.

Rhabdomyolysis associated with gemfibrozil-colchicine therapy. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: Interaction between amlodipine and simvastatin in patients with hypercholesterolemia and hypertension. Rhabdomyolysis after addition of digitoxin to chronic simvastatin and amiodarone therapy.

Drug Metabol Drug Interact. Does cholestyramine interfere with cyclosporine absorption? Franco 1,4Y. Potential interaction between troglitazone and atorvastatin. Framacologia the interactions identified in patients on hypolipidemic drugs, Evaluation of the pharmacokinetic interaction between fluvastatin Loa and cyclosporine in renal transplant recipients.


Effect of atorvastatin and pravastatin on platelet inhibition by aspirin and clopidogrel treatment in patients with coronary stent thrombosis.

Effects of rosuvastatin on platelet inhibition by clopidogrel in cardiovascular patients. Pharmacokinetic interaction hipoolipemiantes ezetimibe and lovastatin in healthy volunteers. No effect of rosuvastatin on the pharmacokinetics of digoxin in healthy volunteers.

Fármacos Hipolipemiantes

Effect of gemfibrozil on the pharmacokinetics of pioglitazone. Recently, many pleiotropic effects have been reported with these drugs, such as anti-inflammatory properties, improvement in endothelial function and benefits on hemostasis. Potential interaction between warfarin and fluvastatin. Pharmacokinetic interaction between nelfinavir and pravastatin in HIV-seronegative volunteers: Study of the drug-drug interaction between simvastatin and cisapride in man.

Law M, Rudnicka AR.

Fármacos Hipolipemiantes | Flashcards

Pleiotropic effects of statins: Rhabdomyolysis in association with simvastatin and amiodarone. Amiodarone interacts with simvastatin but not with pravastatin disposition kinetics.

J Pharmacol Exp Ther. Therefore, statins metabolized through CYP3A4 simvastatin, lovastatin and atorvastatin are the ones with the highest number of clinically relevant interactions. Baycol withdrawn from market.


Interaction between enfuvirtide, an injectable fusion inhibitor, and niacin in an HIV-infected patient. Effect of the bile acid sequestrant colesevelam on the pharmacokinetics of pioglitazone, repaglinide, estrogen estradiol, norethindrone, levothyroxine, and glyburide. Expert Opin Investig Drugs. Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion. Fibrates in the treatment of dyslipidemias-time for a reassessment. CYP2C8 activity recovers within 96 hours after gemfibrozil dosing: Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin.

Gemfibrozil markedly increases the plasma concentrations of montelukast: Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine. Eur J Clin Invest.

The effect of fluconazole on the pharmacokinetics of rosuvastatin.