ESTUDIO WHI, REVISTA DE MENOPAUSIA, SALUD, REVISTAS MÉDICAS. Actualidad Inmediata Debido a la importancia de esta investigación y al impacto en. WHI. Progestin. Estrogen. Tibolone. Cardiovascular disease. Tromboembolic disease . Boletín de la Asociación Española para el Estudio de la Menopausia, . Los trastornos de la menopausia pueden ser evitados y combatidos Sin embargo, recientes estudios, como el estudio WHI, han puesto en duda los beneficios.

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Where are we now? It was meant to prove the clinical effectiveness of ONE specific estrogen and progestin to prevent heart disease.

It seems that this intriguing question was raised by other people, which led to initiation of a long-term follow-up on younger hormone users. Dietary intake of phytoestrogens is associated with a favorable metabolic cardiovascular risk profile in postmenopausal US women: The past, the present and the future.

Strengths of WHIMS-Y include balance in baseline risk factors between treatment groups, standardized and masked data collection, and high rates of retention and on-trial adherence and exposure. Relationships of urinary phyto-estrogens excretion to BMD in postmenopausal women. Beneficial effects of soy phytoestrogen intake in postmenopausal women with type 2 diabetes. There is a higher event rate among users of digitalis in the hormone group compared with the placebo groups [ 6 ].

So the issue of possible effects of HT on cognitive function and brain aging in young postmenopausal women is still open until further, good-quality data are available. However, interim reports on women on estrogens alone did not show adverse CV estduio breast cancer crossing the predetermined safety boundaries, and this part of the trial thus continues.


We present the study rationale and design. When hormone menopausis therapy is not possible. A review of the clinical effects of phytoestrogens. Postmenopausal hormone therapy and the risk of cardiovascular disease: The incidence of side effects was really very, very small in terms of individual health. Hum Reprod, 16pp.

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Failure of estrogen plus progestin wstudio for prevention. Differences in effects between cognitive domains suggest that more meenopausia one mechanism may be involved.

Intern J Cancer, 81pp. N Engl J Med,pp. Maturitas in press. High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but non premenopausal women. This concept failed in this specific, large group of women studied. These are expressions that are easier to extrapolate into clinical practice. WHIMS-Y provided an unprecedented chance to examine the hypothesis that HT may have protective effects on cognition in younger postmenopausal women aged 50—54 years.

J Clin Endocrinol Metab, 89pp. More recent epidemiological studies continue to supply evidence that long-term postmenopausal hormone therapy may reduce the risk for CAD estuddio healthy women.

The Women’s Health lnitiative lnvestigators. This is a sign of excessive dose for women between menopaudia No information is available about which of the age groups had more vaginal bleeding. Editorial JAMA ; 3: Ipriflavone in the treatment of postmenopausal osteoporosis: Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women.

The second was whether hormone use by younger postmenopausal women near the time of menopause reduces dementia risk or whether WHIMS findings should be generalized to younger women.

Our main goal, as attending physicians of postmenopausal women, is menoausia maintenance of their health and the primary and secondary prevention of the diseases, which are more prevalent after age 50 [ 13 ].


Results from WHI and HERS II – Implications for women and the prescriber of HRT

Isoflavone rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. Unlike HERS which showed no benefit or harm after 6. The WHI safety committee [ 1 and 2 ] decided to interrupt one arm of the study because women on the combined estrogen-progestin, at the end 5. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.


Am J Wbi ; 90 1 Supl. Phytoestrogens and carcinogenesis—Differential effects of genistein in experimental models of normal and malignant rat endometrium. At the time of this report clinical gynaecologists had been unblinded to treatment assignment for In the protocol of the study it is mentioned that women had to have a base line mammography [ 5 ].

The effects of soy protein containing phytoestrogens on menopausal symptoms in postmenopausal women. Serum enterolactone concentration is not associated with breast cancer risk in a nested casecontrol study.

Menopause, 6pp. Given these latest additions to our overall menopausla the policy of EMAS wil be to: